AbExp web interface

Enter variant(s):

You can submit up to 10 variants at once, one per line, in one of the following formats (the chr prefix is optional, examples for hg38):

chr3:152269093:G>A
chr8-140300616-T-G
chr17 10631737 C G

Genome version: hg19 hg38

This website provides an interface for running AbExp on arbitrary variants. AbExp is a method that predicts aberrant gene expression across human tissues (Hölzlwimmer et al., bioRxiv) by integrating various variant annotations with tissue-specific isoform proportions and expression variability. The predicted AbExp score shows how much the gene expression is above or below the average population, measured in standard deviations.

Please also check our GitHub repository. Do not hesitate to ask questions and report any bugs in the Issues section on GitHub.

The web interface is based on the AbSplice web interface, and was developed by Georgios Tsitsiridis under the supervision of Florian Hölzlwimmer and Prof. Dr. Julien Gagneur at Gagneur Lab